Wang et al. [47] confirmed elevated levels of lncRNA CASC19 and downregulation of miR-301b-3p in NSCLC cells and reported that CASC19 depletion accelerated cell apoptosis and suppressed cancer progression by repressing the expression of Bcl-2 and increasing the level of cleaved caspase-3, cleaved caspase-6 and cleaved PARP by sponging miR-301b-3p and modulating its downstream target LDLR. This evidence concerns the gene CASP3 and cancer.