For example, low expression of the lncRNA PANDAR predicted a poor prognosis of NSCLC and increased tumour cell proliferation by affecting the expression of the Bcl-2 protein family (Bax, Bad and Bcl-2) and caspase-3 via interaction with NF-YA at the transcriptional level [35]. The gene discussed is CASP3; the disease is non-small cell lung carcinoma.