CD8A and cancer: An analysis of infiltrating immune cells revealed that the high infiltration of CD8+CD161+ T cells, largely comprising MAIT cells, type 17 CD8+ T cells (Tc17 cells), and stem cell-like memory cells, in tumors represented a favorable prognostic signature across a wide array of human cancers (Gentles et al., 2015; Konduri et al., 2021).