Also, the correlation between the expression of hsa_circRNA_101328 and RA clinical laboratory indexes was analyzed, and the results showed that hsa_circRNA_101328 had a significantly negative correlation with CRP and no correlation with RF, CCP, ESR, platelet aggregation, platelet count, lymphocyte count, neutrophil count, leukocyte count, lymphocyte percentage and central granulocyte percentage. This evidence concerns the gene CRP and rheumatoid arthritis.