It was also found that the aqueous humour levels of TGF-β1 and TGF-β2 were evaluated in the eyes of patients with acute primary angle closure [12], and the TGF-β2 concentration was significantly elevated in patients with concurrent open-angle glaucoma, and complicating diabetes [13–16], as well as in patients with neovascular glaucoma secondary to proliferative diabetic retinopathy [17]. This evidence concerns the gene TGFB1 and proliferative diabetic retinopathy.