APOE and Alzheimer disease: In sensitivity analyses, models using APOE ε4 allele count showed similar patterns to the main analysis (eAppendixes 6 and 7 and eTables 7-10 in the Supplement), and models using the AD-GRSs that omitted APOE ε4 had attenuated modification of age associations compared with the main analysis (eAppendix 8 and eTables 11 and 12 in the Supplement).