A VDJdb database (Shugay et al., 2018; Bagaev et al., 2020) search identified cluster-related clonotypes that are highly similar or identical to known TCRβ variants specific to the HLA-A*02-restricted melanoma-associated antigens Melan-A (Melan-Aaa26-35 - ELAGIGILTV) and NY-ESO-1 (NY-ESO-1aa157-165 - SLLMWITQC) in 20% and 50% of patients from the Riaz et al., 2017; Tumeh et al., 2014, cohorts, respectively. This evidence concerns the gene HLA-A and melanoma.