One group reported that TRIM29 mediates the ubiquitination of stimulator of interferon genes (STING) and the STING‐TBK1‐IRF3 signalling pathway, thereby inhibiting interferon‐I and pro‐inflammatory cytokine production, which contributes to the essential roles of TRIM29 in many autoimmune diseases, including IBD.105. The gene discussed is TRIM29; the disease is autoimmune disease.