After analyzing the correlation between TFRC and immunophenotype, to further explore the relationship between TFRC and immunotherapy, we firstly calculated the immune cells infiltrating the tumor microenvironment on the strength of bulk RNA-seq data by using several algorithms (TIMER, CIBERSORT, quantiseq, MCPcounter, xCell, and EPIC) (Figure 9A). This evidence concerns the gene TFRC and neoplasm.