The expression levels of the top ten upregulated (EIF1AY, USP9Y, UTY, ERAP2, IMPAD1, PPBP, HBA2, HBB, TM4SF19, EGFL6) and downregulated (PKGD1L1, LINC00917, IL6, MIR21, DUSP1, CD69, PTGS2, FOS, FOSB, EGR1) genes in OSA are shown in the heatmap in Figure 1B. The gene discussed is TM4SF19; the disease is obstructive sleep apnea syndrome.