Interestingly, AREG, ATF3, ZFP36, and DUSP1 were all associated with inflammation and cancer, specifically enrichment of adipocytokine signaling, bladder cancer, epithelial cell signaling in Helicobacter pylori infection, and JAK/STAT signaling pathways in patients with high AREG expression (Figure 7A). This evidence concerns the gene DUSP1 and urinary bladder carcinoma.