The AUCs of FOS, IL6, ATF3, JUN, DUSP1, EGR1, PTGS2, FOSB, CXCL2, NR4A1, SOCS3, ZFP36, NR4A2, KLF4, AREG, and CD69 were all >0.7 (Figure 3), indicating that they might be useful diagnostic biomarkers for OSA. The gene discussed is KLF4; the disease is obstructive sleep apnea syndrome.