The expression levels of the top ten upregulated (EIF1AY, USP9Y, UTY, ERAP2, IMPAD1, PPBP, HBA2, HBB, TM4SF19, EGFL6) and downregulated (PKGD1L1, LINC00917, IL6, MIR21, DUSP1, CD69, PTGS2, FOS, FOSB, EGR1) genes in OSA are shown in the heatmap in Figure 1B. This evidence concerns the gene CD69 and obstructive sleep apnea syndrome.