AKT1 and cancer: These biological functions and pathways included angiogenesis, cellular response to growth factor stimulus, heparin-binding, kidney development, mononuclear cell differentiation, pathways in cancer, response to calcium ion, HIF (hypoxia-inducible factor)-1 signaling pathway, IL-17 signaling pathway, and PI3K-Akt signaling pathway (Figures 2A,C; Table 2, Supplementary Tables 5, 6).