MYCN and neuroblastoma: The potential clinical significance of the present study included: (1) radiomics based on pre-therapy 18F-FDG PET/CT provides a relatively accurate method in a non-invasive way for predicting MYCN, 1p and 11q, which can be applicable to pediatric NB patients; (2) the status of MYCN, 1p and 11q can be used for risk stratification, therapy selection, therapy response monitor and prognosis prediction.