Thus, the CD5 rs2241002C allele and the minor CD5 rs2241002T-rs2229177C haplotype, previously associated with a more aggressive form of SLE (lupus nephritis) (39), showed association with anti-Ro/anti-La antibody positivity, and with anemia and thrombocytopenia, respectively. The gene discussed is SSB; the disease is anemia (phenotype).