The fully adjusted regression model demonstrated that the increased SII scores were closely associated with higher levels of Scr elevation (β = 0.315, 95% CI: [0.206 to 0.424], P < 0.001), after adjusting age, sexw, diabetes, hypertension, eGFR, type and volume of contrast agent, EF, CRP, and medications (statin, furosemide injection and dopamine). This evidence concerns the gene CRP and hypertensive disorder.