Based on the KEGG database, we further explored the correlation between the functional pathway of HCC-MVI microbiome and the positive rate of M2-type TAM in TME, and the mTOR signaling pathway was found to be positively correlated with a positive rate of M2-type TAM in TME (correlation coefficient 0.37, P = 0.01; Table 2). The gene discussed is MTOR; the disease is hepatocellular carcinoma.