Correlations were moderately close between SMC5 and CD8+ T cells, M1 macrophages, neutrophils, Th2 cells, Tregs, and monocytes, and very close between SMC6 and B cells, M2 macrophages, Th2, Tregs, and monocyte markers in patients with PAAD. The gene discussed is CD8A; the disease is pancreatic adenocarcinoma.