As illustrated in Figure 10A and Supplementary Table S12, NOP2 expression was positively related to the TMB in 15 of 33 cancers, including ACC, BLCA, BRCA, COAD, HNSC, KICH, KIRC, LGG, LIHC, LUAD, LUSC, PRAD, READ, STAD, and UCEC, whereas a negative association was found in CHOL and THYM. This evidence concerns the gene NOP2 and cancer.