TARDBP and amyotrophic lateral sclerosis: Similarly, TDP-43 inclusions are found in the glial cells of both gray and white matter spinal cord, in sALS and some fALS patients (Arai et al., 2006; Mackenzie et al., 2007; Brettschneider et al., 2013) suggesting the important role of glial cells in ALS pathology (Vahsen et al., 2021).