Many ALS-linked proteins, including FUS, TDP-43, TIA-1, hnRNPA1, Ataxin-2, C9orf72 repeats have all been shown to localize in SGs (Nonhoff et al., 2007; Bentmann et al., 2012; Dewey et al., 2012; Li et al., 2013; Ramaswami et al., 2013; Boeynaems et al., 2017). The gene discussed is TARDBP; the disease is amyotrophic lateral sclerosis.