Although the infection rates were different for the small cell number deeply sequenced dataset (Deep dataset) and large cell number scRNA-seq dataset (Large dataset), unsupervised cell clustering revealed one cluster “HR-IvL,” which had a high ratio of infected cells vs. cellslow parasite reads (363 infected cells vs. 45 cellslow parasite reads) in the Large dataset (Supplementary Figures S2A, B and Table S1B). Here, IVL is linked to infection.