Figure 2C shows the detection of gelatinolytic bands for MMP-2 (62 kDa) and MMP-9 (88 kDa) on SDS-PAGE gel. Densitometry analysis (Figure 2D) shows that both enzymes MMP-2 and MMP-9 are significantly more active in CCC heart tissue samples as compared to both control and/or DCM samples. Here, MMP9 is linked to familial dilated cardiomyopathy.