Patients: 24 adults with obesity and mild to moderate insulin resistance were randomized to lean donor cFMT (n = 12) vs. placebo capsule (n = 12).Primary outcome(s): change in insulin sensitivity at 6 weeks.Secondary outcome(s): HbA1C, body weight, body composition, and resting energy expenditure was assessed at 6 and 12 weeks. The gene discussed is INS; the disease is Insulin resistance.