We identified 3 SNPs (rs10519613, rs4819554, and rs4149570) and 5 SNPs (rs10519613, rs4819554, rs2070600, rs755622, and rs4149570) in inflammation genes that were prognostic indicators for PFS and OS of advanced NSCLC treated with EGFR-TKIs, respectively. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.