Given that several molecules positively correlated with immune cell infiltration, such as, APOBEC3B and TNFSF13, have been reported as potential biomarkers in gliomas (75, 76), to ensure our findings, we utilized the TIMER, ESTIMATE and CIBERSORT algorithms to further assess the association between MD2 expression and immune cells infiltration. This evidence concerns the gene TNFSF13 and central nervous system cancer.