Recent research has shown that immune checkpoint inhibitors in combination with chemotherapy may alleviate disease progression.<h4>Case summary</h4>A 45-year-old female patient with gallbladder cancer accompanied by multiple abdominal lymph node metastasis was treated with camrelizumab combined with paclitaxel for injection (albumin-bound) and gemcitabine (AG) to downstage the tumor before a radical surgery could be performed. The gene discussed is ALB; the disease is gallbladder cancer.