In this study, we found that PLIN2 in the invasive front was an independent risk factor for shorter MFS and CD68+TAMs were the main resource of PLIN2 in OSCC; thus, we speculated that the correlation between CD68+TAMs and outcome of tumor was distinct between TAM subsets or intratumoral distribution of TAMs (38). The gene discussed is PLIN2; the disease is neoplasm.