As for individuals affected by ganglioglioma, we observed that 25% of them presented alterations involving BRAF and PIK3CA, while 50% displayed amplification of CDK4, KIT and PDGFRA. Finally, the single case of diffuse midline glioma (case 37) showed a concomitant truncated form and CNA loss of RB1 and a CNA gain of KIT and PDGFRA. Here, CDK4 is linked to diffuse midline glioma.