In respect of UTUC, high SFRP2 expression in stroma but not in tumors was unfavorably prognostic for both disease-specific survival (DSS) and metastasis-free survival (MeFS) (both p < 0.0001) in the univariate analysis (Table 4 and Figures 4A–D). Here, SFRP2 is linked to renal pelvis/ureter urothelial carcinoma.