ST6GAL1 and acute lymphoblastic leukemia: To investigate whether or not increased ST6Gal1 expression can contribute to a more malignant phenotype in cells that initially have relatively lower expression, we transduced US7 BCP-ALL cells with a vector encoding human ST6Gal1 (Supplementary Figure 1A) or with the empty vector, then flow-sorted cells to obtain a homogenous population.