Concerning the GO pathway enrichment results, we found that mRNA processing was positively correlated with the expression level of both ALKBH2 and ALKBH8, and immune response was negatively correlated with ALKBH2/8 expression level, which might partly explain the worse survival of GBM patients with higher transcription levels of ALKBH2/8 (Figures 8A, B). This evidence concerns the gene ALKBH2 and glioblastoma.