IFNB1 and neoplasm: The GSEA analysis reaffirmed the crucial role of ITGA5 in carcinogenesis and shaping tumor immune microenvironment, nicely exemplified by priming the regulation of T cell proliferation, regulation of macrophage chemotaxis, response to interferon-beta, apoptosis, antigen processing and presentation, natural killer cell-mediated cytotoxicity (Figure 3C).