Moreover, the time-dependent receiver operating characteristic (ROC) curves of ITGA5 exhibited high sensitivity and specificity, which were demonstrated by the 1-, 2-, and 3-year all area under the curves (AUC) were greater than 0.842 in the TCGA gliomas dataset, and greater than 0.726 in the CGGA gliomas dataset, respectively (Figures 2F, G). The gene discussed is ITGA5; the disease is central nervous system cancer.