Moreover, the time-dependent receiver operating characteristic (ROC) curves of ITGA5 exhibited high sensitivity and specificity, which were demonstrated by the 1-, 2-, and 3-year all area under the curves (AUC) were greater than 0.842 in the TCGA gliomas dataset, and greater than 0.726 in the CGGA gliomas dataset, respectively (Figures 2F, G). This evidence concerns the gene ITGA5 and glioma.