Next, we analyzed the expression profiles of ADAM8 and miR-181a-5p in several GBM cell lines, including U87, U251, G112, G28, three primary patient-derived cell lines GBM42, GBM29, GBM98, and three patient-derived Glioblastoma stem-like cell lines (GSCs), 2016/240, 2017/151 and 2017/74 (Figures 1F, G). The gene discussed is ADAM8; the disease is glioblastoma.