Data are presented as median (percentiles 25-75) or as % (n).BMI: body mass index; CHO: carbohydrate; DBP: diastolic blood pressure; HbA1c: hemoglobin A1c; HDL: high-density lipoprotein cholesterol; HR: heart rate; hs-CRP: high-sensitivity C-reactive protein; HT: hypertension; LDL: low-density lipoprotein cholesterol; non-HDL: non-high-density lipoprotein cholesterol; SBP: systolic blood pressure; TC: total cholesterol; TDID: total daily insulin dose; TG: triglycerides; WC: waist circumference; WHR: waist-hip ratio. The gene discussed is INS; the disease is Hypertension.