The authors also reported similar association with ischemic stroke for both troponins and proposed some theories to explain the unexpected differences found between the two troponins, including the transiently expression in fetal skeletal muscle of cTn-T, as well as the different upstream genetic determinants (some of the genes associated with cTnT are highly abundant in cardiac z-disc structures, while for cTnI, the most important genes are part of the kallikrein-kinin axis and loci have been associated with vasoactive peptides). Here, TNNT2 is linked to ischemic stroke.