Six immune subtypes defined to measure immune infiltrates in tumor immune response, numbered from lowest to the highest relative abundance of cytotoxic cells, were C1 (wound healing), C2 (INF-γ dominant), C3 (inflammatory), C4 (lymphocyte depleted), C5 (immunologically quiet), and C6 (TGF-β dominant) 19. This evidence concerns the gene TGFB1 and neoplasm.