Lheureux S et al. 16 reported that the results of the clinical trial study of anti-CTLA-4 monoclonal antibody ipilimumab for metastatic or recurrent cervical cancer showed that 42 patients with cervical cancer previously treated with radiotherapy or chemotherapy received ipilimumab, of the 34 evaluable patients, 1 had partial response, 10 had stable disease, 23 had progressive disease. The gene discussed is CTLA4; the disease is cervical cancer.