Renal inflammation progressed over time in untreated rats, reaching statistically significant values after 30 days of CKD in all analyzed parameters (153 ± 35 for CD68, 132 ± 30 for CD3 and 135 ± 27 for PCNA vs. 36 ± 7, 14 ± 3, and 24 ± 3, respectively, p < 0.05). The gene discussed is PCNA; the disease is chronic kidney disease.