Emerging topics in this field mainly include the study of CAR-T cells in glioblastoma (related targets: IL13Rα2, EGFRvIII, and HER2), neuroblastoma (related target: GD2), sarcoma (related target: HER2), and pancreatic cance  (related target: mesothelin), especially glioblastoma. The gene discussed is ERBB2; the disease is neuroblastoma.