In order to exclude the possible role of non-desmoglein Abs whose concentration could also have been increased after adjustment of the anti-DSG3 IgG titer, we previously checked that the sera collected from this patient both at baseline and at the time of CR did not contain anti-Dsc3 (desmocollin 3), anti-SPCA1 (secretory pathway Ca2+/Mn2+-ATPase isoform 1), or anti-CHRM3 (cholinergic receptor muscarinic 3) Abs, which have been reported to be involved in the pathogenicity of pemphigus patients (25, 26). The gene discussed is DSG3; the disease is pemphigus.