C4A and cryoglobulinemia: Among the SVR patients with baseline cryoglobulinemia, compared with baseline levels, at 12 weeks posttherapy, C3 and C4 levels increased and IgG, IgM and RF levels decreased for those without 12-week posttherapy cryoglobulinemia; at 24 and 48 weeks posttherapy, C4 levels increased and IgG and IgM levels decreased for those without cryoglobulinemia until 48 weeks posttherapy (Supplementary Table 4).