n SVR patients, baseline IgM levels were independently associated with 12-week and 24-week posttherapy cryoglobulinemia (Supplementary Tables 5, 6), baseline BMI and IgM levels were independently associated with 48-week posttherapy cryoglobulinemia (Table 3), and baseline TC and IgM levels were independently associated with 4-year posttherapy cryoglobulinemia (Table 4). The gene discussed is CD40LG; the disease is cryoglobulinemia.