IGHE and allergic asthma: These cytokines play an important role in allergic asthma by promoting the production of immunoglobulin E (IgE) as well as a large number of inflammatory mediators and then cause airway inflammation (7, 8) The current treatments for allergic asthma show potential side effects and are not effective for all patients, which caused the incidence and complications of allergic asthma to increase dramatically over the past decade (9), so there is an urgent need for novel treatment strategies for allergic asthma.