As is shown in Table 2, univariate analysis revealed that age, ECOG PS, Subtype, B symptoms, primary tumor invasion, number of extranodal sites, regional lymphadenopathy invasion, LDH level, Ann-Arbor stage, expression status of CD56, IPI score and KPI score correlated significantly with both OS and PFS. The gene discussed is NCAM1; the disease is neoplasm.