VEGFA and age-related macular degeneration: Although PDGF-BB could be induced by hypoxia and a previous study showed that combined suppression of VEGF and PDGF-BB provided superior outcomes versus suppression of VEGF alone in an early-phase clinical trial in patients with exudative AMD (39), our study showed higher levels of PDGF-BB in the AMD and RVO groups, but there was no significance.