CHRM1 and colon adenocarcinoma: To clarify the relationship between CHRM1 and components of the β-catenin pathway and gauge the potential for functional MR-induced effects on β-catenin signaling, a subset of 72 genes previously identified to be downstream of β-catenin signaling and curated in our dataset were analyzed in normal colon vs. primary colon adenocarcinoma tissues (Herbst et al., 2014).