Recent studies also demonstrated that CHIT1 is dysregulated in lung diseases characterized by inflammation and remodeling such as bacterial infection, asthma, COPD and pulmonary fibrosis (Lee et al., 2012; Cho et al., 2015; James et al., 2016; Hong et al., 2018; Sharma et al., 2018; Lee et al., 2019). This evidence concerns the gene CHIT1 and chronic obstructive pulmonary disease.