HOTAIR and colorectal carcinoma: Liu et al. identified 144 lncRNAs differentially expressed in metastatic CRC patients compared with nonmetastatic CRC patients from The Cancer Genome Atlas (TCGA) database, and finally identified a 3-lncRNA signature (LINC00114, LINC00261, and HOTAIR) with the greatest prognostic value for CRC (Shuzhen Liu et al., 2020).