Other studies showed that Linc01578 facilitated the metastasis of colon cancer by forming a positive feedback loop with NF-κB/YY1 and suggested Linc01578 as a potential biomarker for prognosis and therapeutic target for colon cancer metastasis (Jia Liu et al., 2020). This evidence concerns the gene NFKB1 and malignant colon neoplasm.