As for the relative Linc01836 expression in serum samples, the cutoff value was defined as 1.63, offering sensitivity of 65.0% and specificity of 87.0%, and the accuracy of differentiating CRC from a healthy population could reach 76.0%, which was superior to CEA (73.8%), Cyfra21-1 (68.7%), CA19-9 (59.3%), and CA72-4 (53.1%). The gene discussed is CEACAM5; the disease is colorectal carcinoma.