STK39 and intrahepatic cholestasis: To determine the molecular mechanisms by which DCHT exerts its protective effect on acute intrahepatic cholestasis induced-liver injury, we exploited the GeneCards and DisGeNET databases which identified 42 putative targets involved in DCHT treatment for intrahepatic cholestasis (Figure 4A and Supplementary Table S4) and applied KEGG pathway enrichment analysis to the DCHT target data (Figure 4B).