And ClueGO was used to construct pathways enrichment network for the core targets, and the pathways enrichment includes Schwann cell differentiation, p53 signaling pathway, response to antibiotic, Pertussis, Small cell lung cancer, IL-17 signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, response to nicotine, AGE-RAGE signaling pathway in diabetic complications. Here, TP53 is linked to small cell lung carcinoma.