Impairment of platelet-derived growth factor (PDGF) receptor α (PDGFRA) and the resultant mutation in the 3′ untranslated region (UTR) of the PDGFRA gene (c.*34G > A) is associated with cleft palate in humans, mice, and zebrafish (Xu et al., 2005; Eberhart et al., 2008; Rattanasopha et al., 2012). The gene discussed is PDGFRA; the disease is cleft palate.