As shown in Figure 8, the area under the ROC curve (AUC) reached 0.949 [95% confidence interval (CI): 87.3–100%], and plasma chemerin had a satisfactory sensitivity (85.7%) and specificity (100%) at a concentration of 471.76 pg/ml (p<0.001), which indicated considerable diagnostic value for IPAH. This evidence concerns the gene RARRES2 and idiopathic pulmonary arterial hypertension.