In Figure 9A, IHC staining showed that, after treatment with FPS or RAP, the immunostaining of NLRP3, ASC, and Caspase-1 in glomeruli in these DKD model rats were significantly decreased in the FPS and RAP group rats when compared to the Vehicle group rats (Figures 9B–D). Here, NLRP3 is linked to diabetic kidney disease.