Univariate Cox regression analyses found that ALP ≥ 187.5 IU/L (P<0.001; HR=6.694), GGT ≥ 85 IU/L (P=0.013; HR=2.767), EF < 50% (P=0.023; HR=2.809), TBIL ≥ 20 μmol/L (P=0.019; HR=3.698), CTNI ≥ 0.1 ng/mL (P=0.016; HR=2.792), ITE < VGPR (P=0.002; HR=6.711), and BU staging system stage ≥ III (P=0.004; HR=3.431) were related to the prognosis of AL-PCMM and AL-MM. This evidence concerns the gene TNNI3 and Miyoshi myopathy.